Third-generation sequencing

Third-generation sequencing

By Gregory Snyder Since the completion of the Human Genome Project less than a decade ago, the cost of sequencing genomes has decreased more than…

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The myriad throng: Human effective population size

The myriad throng: Human effective population size

Economy recapitulates demography? (image source) Iranians count their rials in superunits of the toman, from a Mongol word for ten thousand soldiers. Remarkably, such a…

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Rare variants, disease, and population size

Rare variants, disease, and population size

Three new papers spotlight a glut of rare variants in our genomes, with key insights for human history and health.

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Why cancers are the least — and most — genetic of diseases

Why cancers are the least — and most — genetic of diseases

The plot thickens. The crab […] only runs backwards. – Arsenio Rodríguez, Cangrejo Fue a Estudiar In time, finer data and statistical models will test…

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On twins, genomes, and health

On twins, genomes, and health

Twins have sometimes no resemblance to each other. – Aristotle, The History of Animals A much-discussed new paper from Nicholas Roberts, Bert Vogelstein, and colleagues…

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